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Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology Jul 1, 2025

Intracellular calcium (Ca) release via phospholipase C (PLC) following G-protein-coupled receptor (GPCR) activation is typically linked to membrane depolarization and airway smooth muscle (ASM) contraction. However, recent findings show that bitter t...

Humans Animals Receptors, G-Protein-Coupled Calcium Myocytes, Smooth Muscle Respiratory System Calcium Signaling Muscle, Smooth Chloroquine Taste Receptors, Type 2 Histamine Flufenamic Acid

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Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle.

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AIMC Topic: Myocytes, Smooth Muscle

Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle.

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