AIMC Topic: Calcium
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Development of a deep learning based approach for multi-material decomposition in spectral CT: a proof of principle in silico study.
Scientific reports
Aug 6, 2025
Conventional approaches to material decomposition in spectral CT face challenges related to precise algorithm calibration across imaged conditions and low signal quality caused by variable object size and reduced dose. In this proof-of-principle stud...
CalTrig: A GUI-Based Machine Learning Approach for Decoding Neuronal Calcium Transients in Freely Moving Rodents.
eNeuro
Jul 15, 2025
Advances in in vivo Ca imaging using miniature microscopes have enabled researchers to study single-neuron activity in freely moving animals. Tools such as Minian and CalmAn have been developed to convert Ca visual signals to numerical data, collecti...
Incidental Finding of Coronary and Non-Coronary Artery Calcium: What Do Clinicians Need To Know?
Current atherosclerosis reports
Jul 12, 2025
PURPOSE OF REVIEW: This review summarizes the role of incidentally and non-incidentally discovered coronary artery calcification (CAC) and the evolving role of non-coronary artery calcification in atherosclerotic cardiovascular disease (ASCVD) risk a...
Diffusion-based image translation model from low-dose chest CT to calcium scoring CT with random point sampling.
Computers in biology and medicine
Jun 7, 2025
BACKGROUND: Coronary artery calcium (CAC) scoring is an important method for cardiovascular risk assessment. While artificial intelligence (AI) has been applied to automate CAC scoring in calcium scoring computed tomography (CSCT), its application to...
Evaluating safe infrared neural stimulation parameters: Calcium dynamics and excitotoxicity thresholds in dorsal root ganglia neurons.
Journal of neuroscience methods
May 16, 2025
BACKGROUND: As a promising neural stimulation technique, infrared neural stimulation (INS) has recently gained significant attention due to its ability to stimulate neuronal activities without needing exogenous agents. NIR light is absorbed by water ...
AI-enabled opportunistic measurement of liver steatosis in coronary artery calcium scans predicts cardiovascular events and all-cause mortality: an AI-CVD study within the Multi-Ethnic Study of Atherosclerosis (MESA).
BMJ open diabetes research & care
Apr 12, 2025
INTRODUCTION: About one-third of adults in the USA have some grade of hepatic steatosis. Coronary artery calcium (CAC) scans contain more information than currently reported. We previously reported new artificial intelligence (AI) algorithms applied ...
Advanced SERSome-based artificial-intelligence technology for identifying medicinal and edible homologs.
Talanta
Mar 12, 2025
Medicinal and edible homologs (MEHs) offer significant preventive and therapeutic benefits for various diseases and health functions. However, the widespread application of MEHs faces significant challenges, particularly in quality control and rapid ...
Living Microalgae-Based Magnetic Microrobots for Calcium Overload and Photodynamic Synergetic Cancer Therapy.
Advanced healthcare materials
Feb 27, 2025
The combination of Ca overload and reactive oxygen species (ROS) production for cancer therapy offers a superior solution to the lack of specificity in traditional antitumor strategies. However, current therapeutic platforms for this strategy are pri...
Machine Learning-Driven Discovery of Structurally Related Natural Products as Activators of the Cardiac Calcium Pump SERCA2a.
ChemMedChem
Feb 6, 2025
A key molecular dysfunction in heart failure is the reduced activity of the cardiac sarcoplasmic reticulum Ca-ATPase (SERCA2a) in cardiac muscle cells. Reactivating SERCA2a improves cardiac function in heart failure models, making it a validated targ...
CaBind_MCNN: Identifying Potential Calcium Channel Blocker Targets by Predicting Calcium-Binding Sites in Ion Channels and Ion Transporters Using Protein Language Models and Multiscale Feature Extraction.
Journal of chemical information and modeling
Feb 6, 2025
Calcium ions (Ca) are crucial for various physiological processes, including neurotransmission and cardiac function. Dysregulation of Ca homeostasis can lead to serious health conditions such as cardiac arrhythmias and hypertension. Ion channels and ...
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