AIMC Topic: Muscle, Smooth

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Combined colour deconvolution and artificial intelligence approach for region-selective immunohistochemical labelling quantification: The example of alpha smooth muscle actin in mouse kidney.

Journal of biophotonics
Immunohistochemical (IHC) localisation of protein expression is a widely used tool in pathology. This is semi-quantitative and exhibits substantial intra- and inter-observer variability. Digital approaches based on stain quantification applied to IHC...

Deep learning for histopathological segmentation of smooth muscle in the urinary bladder.

BMC medical informatics and decision making
BACKGROUND: Histological assessment of smooth muscle is a critical step particularly in staging malignant tumors in various internal organs including  the urinary bladder. Nonetheless, manual segmentation and classification of muscular tissues by pat...

Classification of cardiovascular tissues using LBP based descriptors and a cascade SVM.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Histological images have characteristics, such as texture, shape, colour and spatial structure, that permit the differentiation of each fundamental tissue and organ. Texture is one of the most discriminative features. The au...

Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology
Intracellular calcium (Ca) release via phospholipase C (PLC) following G-protein-coupled receptor (GPCR) activation is typically linked to membrane depolarization and airway smooth muscle (ASM) contraction. However, recent findings show that bitter t...