AIMC Topic: Phase Separation

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Machine Learning Diagnostic Model for Hepatocellular Carcinoma Based on Liquid-Liquid Phase Separation and Ferroptosis-Related Genes.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology Oct 7, 2024
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) represents a primary liver malignancy with a multifaceted molecular landscape. The interplay between liquid-liquid phase separation (LLPS) and ferroptosis-a regulated form of cell death-has garnered int...
Humans Machine Learning Prognosis Gene Expression Profiling Liver Neoplasms Carcinoma, Hepatocellular Gene Expression Regulation, Neoplastic Membrane Proteins Ferroptosis Phase Separation GTP Phosphohydrolases
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A two-task predictor for discovering phase separation proteins and their undergoing mechanism.

Briefings in bioinformatics Sep 23, 2024
Liquid-liquid phase separation (LLPS) is one of the mechanisms mediating the compartmentalization of macromolecules (proteins and nucleic acids) in cells, forming biomolecular condensates or membraneless organelles. Consequently, the systematic ident...
Neural Networks, Computer Algorithms Computational Biology Proteins Biomolecular Condensates Phase Separation
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