AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Protein Unfolding

Showing 1 to 4 of 4 articles

Clear Filters

Reconstruction of ARNT PAS-B Unfolding Pathways by Steered Molecular Dynamics and Artificial Neural Networks.

Journal of chemical theory and computation 33780250
Several experimental studies indicated that large conformational changes, including partial domain unfolding, have a role in the functional mechanisms of the basic helix loop helix Per/ARNT/SIM (bHLH-PAS) transcription factors. Recently, single-molec...
Basic Helix-Loop-Helix Transcription Factors Microscopy, Atomic Force Molecular Dynamics Simulation Neural Networks, Computer Protein Conformation Protein Unfolding
View on PubMed DOI

Statistical Learning from Single-Molecule Experiments: Support Vector Machines and Expectation-Maximization Approaches to Understanding Protein Unfolding Data.

The journal of physical chemistry. B 34075752
Single-molecule force spectroscopy has become a powerful tool for the exploration of dynamic processes that involve proteins; yet, meaningful interpretation of the experimental data remains challenging. Owing to low signal-to-noise ratio, experimenta...
Models, Molecular Motivation Protein Unfolding Proteins Support Vector Machine
View on PubMed DOI

Ab initio characterization of protein molecular dynamics with AIBMD.

Nature 39506110
Biomolecular dynamics simulation is a fundamental technology for life sciences research, and its usefulness depends on its accuracy and efficiency. Classical molecular dynamics simulation is fast but lacks chemical accuracy. Quantum chemistry methods...
Artificial Intelligence Density Functional Theory Machine Learning Molecular Dynamics Simulation Nuclear Magnetic Resonance, Biomolecular Peptides Protein Conformation Protein Folding Protein Unfolding Proteins Quantum Theory Thermodynamics Time Factors
View on PubMed DOI

Surface-Induced Unfolding Reveals Unique Structural Features and Enhances Machine Learning Classification Models.

Analytical chemistry 40085815
Native ion mobility-mass spectrometry combined with collision-induced unfolding (CIU) is a powerful analytical method for protein characterization, offering insights into structural stability and enabling the differentiation of analytes with similar ...
Animals Cattle Immunoglobulin G Ion Mobility Spectrometry Lactoglobulins Machine Learning Mass Spectrometry Protein Unfolding Serum Albumin, Bovine Surface Properties
View on PubMed DOI
Popular Topics
Recent Journals