AIMC Topic: Pyridoxal Phosphate

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Application of the deep learning algorithm in nutrition research - using serum pyridoxal 5'-phosphate as an example.

Nutrition journal
BACKGROUND: Multivariable linear regression (MLR) models were previously used to predict serum pyridoxal 5'-phosphate (PLP) concentration, the active coenzyme form of vitamin B6, but with low predictability. We developed a deep learning algorithm (DL...

Biochemical algorithm to identify individuals with ALPL variants among subjects with persistent hypophosphatasaemia.

Orphanet journal of rare diseases
BACKGROUND: Hypophosphatasia (HPP) is a rare and underdiagnosed condition characterized by deficient bone and teeth mineralization. The aim of this study was first, to evaluate the diagnostic utility of employing alkaline phosphatase (ALP) threshold ...