AIMC Topic: Receptors, Glucagon
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Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency.
Nature chemistry
May 16, 2024
Several peptide dual agonists of the human glucagon receptor (GCGR) and the glucagon-like peptide-1 receptor (GLP-1R) are in development for the treatment of type 2 diabetes, obesity and their associated complications. Candidates must have high poten...
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