AIMC Topic: Receptors, Steroid

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Deep learning-enabled breast cancer hormonal receptor status determination from base-level H&E stains.

Nature communications Nov 16, 2020
For newly diagnosed breast cancer, estrogen receptor status (ERS) is a key molecular marker used for prognosis and treatment decisions. During clinical management, ERS is determined by pathologists from immunohistochemistry (IHC) staining of biopsied...
Humans Female Breast Neoplasms Deep Learning Staining and Labeling Area Under Curve Neoplasm Grading Receptors, Steroid
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Classification of Human Pregnane X Receptor (hPXR) Activators and Non-Activators by Machine Learning Techniques: A Multifaceted Approach.

Combinatorial chemistry & high throughput screening Jan 1, 2016
The Human Pregnane X Receptor (hPXR) is a regulator of drug metabolising enzymes (DME) and efflux transporters (ET). The prediction of hPXR activators and non-activators has pharmaceutical importance to predict the multiple drug resistance (MDR) and ...
Humans Machine Learning Support Vector Machine Bayes Theorem Drug Interactions Drug Resistance, Multiple Pregnane X Receptor Pregnanes Receptors, Steroid
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