AIMC Topic: Rhodopsins, Microbial

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RhoMax: Computational Prediction of Rhodopsin Absorption Maxima Using Geometric Deep Learning.

Journal of chemical information and modeling Jun 3, 2024
Microbial rhodopsins (MRs) are a diverse and abundant family of photoactive membrane proteins that serve as model systems for biophysical techniques. Optogenetics utilizes genetic engineering to insert specialized proteins into specific neurons or br...
Deep Learning Models, Molecular Amino Acid Sequence Protein Conformation Optogenetics Rhodopsin Rhodopsins, Microbial
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Exploration of natural red-shifted rhodopsins using a machine learning-based Bayesian experimental design.

Communications biology Mar 19, 2021
Microbial rhodopsins are photoreceptive membrane proteins, which are used as molecular tools in optogenetics. Here, a machine learning (ML)-based experimental design method is introduced for screening rhodopsins that are likely to be red-shifted from...
Machine Learning Escherichia coli Databases, Protein Bayes Theorem Color Hydrogen-Ion Concentration Light Amino Acid Sequence Proof of Concept Study Sequence Analysis, Protein Ion Channels Optogenetics Protein Conformation, alpha-Helical Rhodopsins, Microbial
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