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RNA Polymerase Sigma 54

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Computational Prediction of Sigma-54 Promoters in Bacterial Genomes by Integrating Motif Finding and Machine Learning Strategies.

IEEE/ACM transactions on computational biology and bioinformatics 29993815
Sigma factor, as a unit of RNA polymerase holoenzyme, is a critical factor in the process of gene transcriptional regulation. It recognizes the specific DNA sites and brings the core enzyme of RNA polymerase to the upstream regions of target genes. T...
Amino Acid Motifs Base Sequence Computational Biology DNA-Directed RNA Polymerases Escherichia coli Escherichia coli Proteins False Positive Reactions Genome, Bacterial Machine Learning Models, Statistical Promoter Regions, Genetic Reproducibility of Results RNA Polymerase Sigma 54 Software Transcription, Genetic
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ProPr54 web server: predicting σ promoters and regulon with a hybrid convolutional and recurrent deep neural network.

NAR genomics and bioinformatics 39781509
σ serves as an unconventional sigma factor with a distinct mechanism of transcription initiation, which depends on the involvement of a transcription activator. This unique sigma factor σ is indispensable for orchestrating the transcription of genes ...
Bacterial Proteins Binding Sites Genome, Bacterial Internet Neural Networks, Computer Promoter Regions, Genetic Regulon RNA Polymerase Sigma 54 Sigma Factor Software
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