AIMC Topic: RNA Polymerase Sigma 54

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ProPr54 web server: predicting σ promoters and regulon with a hybrid convolutional and recurrent deep neural network.

NAR genomics and bioinformatics Jan 7, 2025
σ serves as an unconventional sigma factor with a distinct mechanism of transcription initiation, which depends on the involvement of a transcription activator. This unique sigma factor σ is indispensable for orchestrating the transcription of genes ...
Neural Networks, Computer Software Bacterial Proteins Internet Promoter Regions, Genetic Binding Sites Genome, Bacterial Sigma Factor Regulon RNA Polymerase Sigma 54
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Computational Prediction of Sigma-54 Promoters in Bacterial Genomes by Integrating Motif Finding and Machine Learning Strategies.

IEEE/ACM transactions on computational biology and bioinformatics Mar 15, 2018
Sigma factor, as a unit of RNA polymerase holoenzyme, is a critical factor in the process of gene transcriptional regulation. It recognizes the specific DNA sites and brings the core enzyme of RNA polymerase to the upstream regions of target genes. T...
Machine Learning Software Reproducibility of Results Computational Biology Escherichia coli Models, Statistical Escherichia coli Proteins Base Sequence False Positive Reactions Promoter Regions, Genetic Transcription, Genetic Genome, Bacterial Amino Acid Motifs DNA-Directed RNA Polymerases RNA Polymerase Sigma 54
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