AIMC Topic: Regulon

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ProPr54 web server: predicting σ promoters and regulon with a hybrid convolutional and recurrent deep neural network.

NAR genomics and bioinformatics Jan 7, 2025
σ serves as an unconventional sigma factor with a distinct mechanism of transcription initiation, which depends on the involvement of a transcription activator. This unique sigma factor σ is indispensable for orchestrating the transcription of genes ...
Neural Networks, Computer Software Bacterial Proteins Internet Promoter Regions, Genetic Binding Sites Genome, Bacterial Sigma Factor Regulon RNA Polymerase Sigma 54
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Application of the random forest algorithm to Streptococcus pyogenes response regulator allele variation: from machine learning to evolutionary models.

Scientific reports Jun 16, 2021
Group A Streptococcus (GAS) is a globally significant bacterial pathogen. The GAS genotyping gold standard characterises the nucleotide variation of emm, which encodes a surface-exposed protein that is recombinogenic and under immune-based selection ...
Humans Machine Learning Algorithms Carrier Proteins Evolution, Molecular Bacterial Proteins Alleles Streptococcal Infections Genetic Variation Streptococcus pyogenes Genes, Bacterial Bacterial Outer Membrane Proteins Antigens, Bacterial Genome, Bacterial Regulon
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Model-to-crop conserved NUE Regulons enhance machine learning predictions of nitrogen use efficiency.

The Plant cell May 9, 2025
Systems biology aims to uncover gene regulatory networks (GRNs) for agricultural traits, but validating them in crops is challenging. We addressed this challenge by learning and validating model-to-crop transcription factor (TF) regulons governing ni...
Machine Learning Gene Regulatory Networks Transcription Factors Zea mays Nitrogen Crops, Agricultural Plant Proteins Gene Expression Regulation, Plant Arabidopsis Regulon
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First steps in automatic summarization of transcription factor properties for RegulonDB: classification of sentences about structural domains and regulated processes.

Database : the journal of biological databases and curation Jan 1, 2017
RegulonDB, http://regulondb.ccg.unam.mx.
Transcription Factors Support Vector Machine Protein Domains Serine Endopeptidases Escherichia coli K12 Databases, Bibliographic Regulon
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