AIMC Topic: Transplantation, Heterologous

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Characterizing the Immune Response in Pig-to-Human Heart Xenografts Using a Multimodal Diagnostic System.

Circulation
BACKGROUND: Porcine genome editing has revolutionized xenotransplantation, recently enabling the first pig-to-human heart xenotransplants. However, the xenoimmune response in heart xenografts remains largely unexplored. This study aimed to precisely ...

Transplant nephropathology: Wherefrom, wherein, and whereto.

Clinical transplantation
Renal pathology is a relatively recent entry in nephrology. While diseases of the kidney are old, their study began in the 19th century with the report of Richard Bright of the lesions of end-stage kidney disease. Its easy diagnosis from albuminuria ...