Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 3,591 to 3,600 of 203,255 articles

Computational modelling of cell identity.

The Biochemical journal
Deciphering cell identity remains a central challenge in biology, as experimental profiling can only capture a fraction of the molecular diversity across human cell states. Computational modelling fills this gap by offering scalable predictions beyon... read more 

Synthesis of Amyloid Images Using a Generative Adversarial Network from 2-Dimensional 18F-FDG Images and Evaluation for Clinical Use.

Journal of nuclear medicine technology
The use of amyloid PET to assess patient suitability of disease-modifying drugs for Alzheimer disease is increasing. This study aimed to synthesize amyloid PET images from 18F-FDG PET images using a generative artificial intelligence algorithm to red... read more 

CodeCytos: AI-assisted spatial molecular imaging analysis via code-augmented agent action space

bioRxiv
Conventional tissue image analysis software provides foundational capabilities for cellular analysis, including segmentation, morphological feature extraction, and spatial organization analysis; however, these tools often require manual intervention ... read more 

SciCore-Omics: a tri-modal foundation model unifying histology, spatial transcriptomics and language for spatial biology

bioRxiv
Histomorphology and spatial transcriptomics capture complementary aspects of tissue biology, but their relationships remain difficult to extract, align, and interpret at scale. Existing foundation models typically connect histology, omics, or languag... read more 

AdventML: Advanced Enzyme Temperature Prediction with Transformer-Based Embeddings and Resampling Strategies

bioRxiv
Accurate prediction of enzymes' optimal catalytic temperature (Topt) is crucial in biotechnology, as enzymes with extreme Topt values are highly desirable for reactions at extreme temperatures and for their general stability. However, experimental de... read more 

HyperNiche: Learning Heterophilic Cellular Niches with Hypergraph Neural Networks

bioRxiv
We propose HyperNiche, a hypergraph-based framework for modeling higher-order, heterogeneous cellular niches from spatial transcriptomics data. Unlike conventional graph-based methods that rely on pairwise similarity and tend to produce homogeneous c... read more 

sstar2: A Python Package for S*-based Archaic Introgression Detection with Machine Learning

bioRxiv
Detecting introgressed genomic fragments from unsampled or extinct source populations remains challenging. The S* statistic is widely used for this purpose, but the original sstar implementation relies on generalized additive models to smooth quantil... read more 

MAGI: Mechanistic Consequences of Genetic Variants via Genomic Foundation Models

bioRxiv
Clinical variant interpretation requires mechanism-aware evidence to guide diagnosis and clarify the biological consequences of mutations. However, existing computational predictors and genomic foundation models largely function as black boxes, provi... read more 

ORIGAMI: Orientation-Aware Graph Neural Network for Assessing Multimeric Interfaces of Protein Complex Structures

bioRxiv
Deep learning-based protein structure prediction methods have led to a paradigm-shift in computational structural biology, yet reliably assessing the quality of computationally predicted multimeric structures remains challenging. Recent methods have ... read more 

ViTAMIn-O: Democratizing computer vision-based machine learning for stem cell research

bioRxiv
Deep Learning (DL) holds exciting potential in automating the prediction of organoid differentiation results. Nevertheless, current models lack adaptability, openness, and robustness in performance. Additionally, broad employments of predictive model... read more