Symptom checkers are apps and websites that assist medical laypeople in diagnosing their symptoms and determining which course of action to take. When evaluating these tools, previous studies primarily used an approach introduced a decade ago that la... read more
BACKGROUND: Renal cell carcinoma (RCC) is a common, often lethal kidney cancer that originates in the renal cortex. Its incidence is rising, and major factors include smoking, obesity, and hypertension, though its etiology is uncertain. While surgery... read more
BACKGROUND: Clinical deterioration in general ward patients is associated with increased morbidity and mortality. Early and appropriate treatments can improve outcomes for such patients. While machine learning (ML) tools have proven successful in the... read more
BACKGROUND: There is a lack of venous thromboembolism (VTE) risk prediction models based on gene expression information. OBJECTIVE: This study aimed to construct a VTE prediction model based on whole blood gene expression profiling, by performing a c... read more
Biomedical physics & engineering express
Jan 16, 2026
Accurate and automatic registration of the pancreas between contrast-enhanced CT (CECT) and non-contrast CT (NCCT) images is crucial for diagnosing and treating pancreatic cancer. However, existing deep learning-based methods remain limited due to in... read more
Objective
Magnetic resonance imaging (MRI)-only proton therapy combines high soft tissue contrast with high-precision dose distributions. However, conventional dose calculation is impossible on MRI due to missing electron density information. Thi... read more
OBJECTIVE: Establishing control and specification limits for Volumetric Modulated Arc Therapy (VMAT) pre-treatment quality assurance (PTQA) is essential for streamlining PTQA workflows and optimizing plan complexity. This study aimed to develop and i... read more
BACKGROUND: Wild-type transthyretin amyloidosis (ATTRwt) is a serious condition. At early stages, symptoms resemble those of heart failure with preserved ejection fraction (HFpEF). Our aim was to perform software-supported nailfold videocapillaroscop... read more
BACKGROUND: Low left ventricular ejection fraction (LEF) can progress undiagnosed. Artificial intelligence-based electrocardiogram (ECG-AI) screening may provide a scalable means to detect LEF. OBJECTIVES: The purpose of this study was to validate a ... read more
Ecotoxicology and environmental safety
Jan 16, 2026
BACKGROUND: Dioxin has emerged as a major and modifiable determinant of tumor burden worldwide. Building on this premise, we investigated whether dioxin-interacting genes (DIGs) are connected to diffuse large B-cell lymphoma (DLBCL) and sought genes ... read more
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