AI Medical Compendium

Stratification of immunotherapy responses by adaptive immune receptor repertoires.

Trends in molecular medicine Jan 20, 2026

A growing number of diseases are now treated with immunotherapies, which consist of interventions that suppress or stimulate the patient's immune system. Because individual humans express a unique repertoire of adaptive immune receptors, the efficacy... read more

Therapeutic nanofibrous scaffolds in precision drug delivery: formulation design, challenges and regulatory frameworks.

Expert opinion on drug delivery Jan 20, 2026

INTRODUCTION: Drug-loaded nanofibrous systems represent a breakthrough in drug delivery, overcoming limitations of conventional formulations. They demonstrate controlled morphology and flexibility across multiple administration routes, with versatili... read more

Microclimates, land cover, and socioeconomic vulnerability shape Anopheles hotspots in Maryland, USA.

Infectious diseases of poverty Jan 20, 2026

BACKGROUND: Anopheles mosquitoes pose notable public health concerns as competent vectors of malaria and other diseases. Although malaria is no longer endemic in the United States, recent locally acquired cases in states including Maryland highlight ... read more

Animals Ecosystem Socioeconomic Factors Malaria Seasons Mosquito Vectors Animal Distribution Maryland Anopheles Microclimate

Advancing cellulose degradation through synthetic biology: engineered pathways and microbial systems for sustainable biomass conversion.

Journal of animal science and biotechnology Jan 20, 2026

Fiber, the most abundant organic polymer in nature, is widely recognized as a foundational sustainable material with diverse applications across industrial, medical, and consumer domains. Owing to its renewability and widespread availability, it also... read more

Shortcomings of deep learning for distributional predictors: a note.

Biostatistics (Oxford, England) Jan 20, 2026

A number of domains in biomedical research use data with a large number of predictors all representing the same type of measurement. Often, an important summary is the within-person distribution of these predictors. Here we focus on settings where th... read more

Humans Neural Networks, Computer Computer Simulation Deep Learning Models, Statistical Data Interpretation, Statistical Bayes Theorem Biostatistics

AI in Patient Care: Evaluating Large Language Model Performance Against Evidence-Based Guidelines for Pulmonary Embolism.

Thoracic research and practice Jan 20, 2026

OBJECTIVE: Artificial intelligence (AI)-driven large language models (LLMs) are increasingly used in patient education; however, their ability to interpret and apply clinical guidelines within real-world physician workflows remains uncertain. Pulmona... read more

Research Paradigm Mismatch: How Patients and Health Care Professionals Seek Health-Related Information Online.

The Permanente journal Jan 20, 2026

INTRODUCTION: Understanding how patients and health care professionals seek and interpret health information online helps to mitigate knowledge gaps at decision points, leading to improved shared decision-making and better health outcomes. The object... read more

BIPE: Artificial Intelligence-Driven Peptide Bitterness Intensity Prediction Engine.

Journal of chemical information and modeling Jan 20, 2026

Bitterness, alongside sour, sweet, umami, and salty tastes, constitutes one of the five basic tastes and serves as a key dimension in shaping food flavor profiles. Food protein processing readily generates bitter peptides, whose intense bitterness of... read more

The Application of Artificial Intelligence to Older Adults With Disabilities: A Scoping Review.

Journal of applied gerontology : the official journal of the Southern Gerontological Society Jan 20, 2026

ObjectiveTo review the application of artificial intelligence (AI) in the care of older adults with disabilities, identifying intervention type, target populations, and effects.MethodsA literature search was performed in the PubMed, Cochrane Library,... read more

Autonomous conversational agents for loneliness, social isolation, depression, and anxiety in older people without cognitive impairment: Systematic review and meta-analysis.

Psychological medicine Jan 20, 2026

Loneliness is a major psychological challenge in older adulthood, contributing to increased risks of depression, anxiety, and mortality. Conversational agents - technologies that interact with users via natural language - have emerged as potential to... read more

Humans Aged Anxiety Depression Robotics Social Isolation Loneliness

Artificial Intelligence Medical Compendium