Hypertrophic cardiomyopathy (HCM), a genetic heart disease defined by unexplained cardiac wall thickening, is a leading cause of sudden death worldwide. However, the three-dimensional organization of cardiac tissue underlying left ventricular hypertr... read more
BACKGROUND: Advances in next-generation sequencing(NGS) and multi-omics approaches reinforced the concept of functional diversity within biofilm communities, revealing roles beyond bacterial taxonomy and highlighting metabolic and ecological mechanis... read more
IEEE transactions on computational biology and bioinformatics
Jan 15, 2026
Viruses are a significant threat to human life, as demonstrated by the global COVID-19 pandemic and the Ebola outbreak. Diseases such as smallpox, AIDS, hepatitis, liver cancer, and cervical cancer often caused by the Human Papillomavirus can lead to... read more
IEEE transactions on pattern analysis and machine intelligence
Jan 15, 2026
With the success of the 3D deep learning models, various perception technologies for autonomous driving have been developed in the LiDAR domain. While these models perform well in the trained source domain, they struggle in unseen domains with a doma... read more
IEEE transactions on pattern analysis and machine intelligence
Jan 15, 2026
Single-photon imaging uses single-photon-sensitive picosecond-resolution sensors to capture 3D structure and supports diverse applications, but success remains mostly limited to simple scenes. In complex scenarios, traditional methods degrade and dee... read more
Accurately predicting how amino acid substitutions alter protein function is a central challenge in biology, with applications from interpreting disease variants to engineering vaccines and therapeutic proteins. We introduce HERMES, a family of fast,... read more
Genome-wide association studies have linked millions of genetic variants to biomedical phenotypes, but their utility has been limited by lack of mechanistic understanding and widespread epistatic interactions. Recently, Transformer models have emerge... read more
Aging, the leading risk factor for numerous diseases, manifests through diverse structural and architectural changes in human tissues, providing an opportunity to quantify and interpret tissue-specific aging. To address this, we present a comprehensi... read more
ObjectiveOur goal was to create open-source software for closed-loop EEG-TMS that allows researchers to rapidly prototype and develop novel stimulation paradigms in a high-level programming language. This addresses the limitations of current solution... read more
Deep visual proteomics (DVP) is an emerging approach for cell type-specific and spatially resolved proteomics. However, its broad adoption has been constrained by the lack of an open-source end-to-end workflow in a community-driven ecosystem. Here, w... read more
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