Development and validation of a machine learning-based, point-of-care risk calculator for post-ERCP pancreatitis and prophylaxis selection.

Journal: Gastrointestinal endoscopy
PMID:

Abstract

BACKGROUND AND AIMS: A robust model of post-ERCP pancreatitis (PEP) risk is not currently available. We aimed to develop a machine learning-based tool for PEP risk prediction to aid in clinical decision making related to periprocedural prophylaxis selection and postprocedural monitoring.

Authors

  • Todd Brenner
    Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
  • Albert Kuo
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.
  • Christina J Sperna Weiland
    Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands.
  • Ayesha Kamal
    Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
  • B Joseph Elmunzer
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina, USA.
  • Hui Luo
    Thoracic Surgery Department, Nan Chong Center Hospital, Nanchong, China.
  • James Buxbaum
    Division of Gastroenterology, University of Southern California, Los Angeles, California, USA.
  • Timothy B Gardner
    Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
  • Shaffer S Mok
    Moffitt Cancer Center, Department of Gastrointestinal Oncology, Division of Gastroenterology, Tampa, Florida.
  • Evan S Fogel
    Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, Indiana.
  • Veit Phillip
    Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Jun-Ho Choi
    Department of Internal Medicine, Dankook University College of Medicine, Dankook University Hospital, Cheonan, Korea.
  • Guan W Lua
    Ministry of Health, Kota Kinabalu, Malaysia.
  • Ching-Chung Lin
    Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
  • D Nageshwar Reddy
    Chairman and Chief Gastroenterologist, Asian institute of Gastroenterology, Hyderabad, India. Electronic address: aigindia@yahoo.co.in.
  • Sundeep Lakhtakia
    Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, 500 082, India.
  • Mahesh K Goenka
    Department of Gastroenterology, Apollo Gleneagles Hospital, Kolkata, India.
  • Rakesh Kochhar
    Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
  • Mouen A Khashab
    Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
  • Erwin J M van Geenen
    Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands.
  • Vikesh K Singh
    Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
  • Cristian Tomasetti
    Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, United States.
  • Venkata S Akshintala
    Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.