Combined use of opioids and other pharmacological therapies used for pain management, such as non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, gabapentinoids, and/or skeletal muscle relaxants (SMRs), in older adult cancer survivors ca...
International journal of pharmaceutics
Oct 23, 2025
Understanding the molecular mechanisms of drug coamorphization remains a key challenge in solid-state pharmaceutics. This study presents a molecular level strategy for designing drug-drug coamorphous systems (CAMs) of apremilast (APR) and aceclofenac...
Oxicams, a major category of nonsteroidal anti-inflammatory drugs, are widely used in daily life. However, excessive consumption of oxicams can pose significant risks to human health. Herein, we introduce an innovative and highly sensitive fluorescen...
Counterfeit drugs are a global issue that has a serious impact on patient morbidity and mortality. Driven by nonspecific cross-reactivity, sensor arrays enable the concurrent discrimination of structurally related drug molecules. Nevertheless, rapidl...
In this paper, we present a predictive model based on artificial neural network (ANN) to evaluate principal physicochemical properties of a set of anti-inflammatory drugs based on chosen topological indices. The molecular descriptors were calculated ...
This study develops and evaluates advanced hybrid machine learning models-ADA-ARD (AdaBoost on ARD Regression), ADA-BRR (AdaBoost on Bayesian Ridge Regression), and ADA-GPR (AdaBoost on Gaussian Process Regression)-optimized via the Black Widow Optim...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Apr 29, 2025
In the pharmaceutical manufacturing industry, continuous production methods have been recognised as providing several benefits compared to traditional batch production. These benefits include increased flexibility, higher product output, enhanced qua...
The improper application of nonsteroidal anti-inflammatory drugs (NSAIDs) presents significant health hazards via vector food contamination. A critical limitation of these traditional existing approaches is their inability to concurrently discern and...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jan 10, 2025
Small molecules as nanomedicine carriers offer advantages in drug loading and preparation. Selecting effective small molecules for stable nanomedicines is challenging. This study used artificial intelligence (AI) to screen drug combinations for self-...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.