AIMC Topic: Point-of-Care Systems

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Minimally Invasive, Label-Free, Point-of-Care Histopathological Diagnostic Platform of Malignant Tumors of the Female Reproductive System Based on Raman Spectroscopy and Machine Learning.

The journal of physical chemistry letters
Fast intraoperative histopathology is critical for optimal surgery in ovarian, endometrial and cervical cancers, yet frozen-section pathology is slow and resource-intensive. We obtained 4750 Raman spectra from 85 human gynecological tissue specimens ...

HepatoAI: Machine-Learning-Assisted Nano-enhanced Point-of-Care System for Personalized Precise Diagnosis of Hepatocellular Carcinoma.

Nano letters
Early diagnosis significantly improves survival rates for hepatocellular carcinoma (HCC), yet traditional methods face limitations, including specialized instruments/personnel and prolonged reporting cycles. While lateral flow immunoassay (LFA) offer...

Entropy-driven signal amplification integrated with machine learning in multiplex lateral flow immunoassay for sensitive Point-of-Care colon cancer diagnosis.

Journal of nanobiotechnology
Investigations on epithelial-mesenchymal transition (EMT) events occurring on circulating tumor cells (CTCs) are poised to significantly advance nanoliquid biopsy methodologies. This study presented a colorimetric multiplex lateral flow immunoassay s...

Machine learning-integrated electrochemical sensing of ciprofloxacin for digital point-of-care therapeutic drug monitoring.

Mikrochimica acta
Timely and precise therapeutic drug monitoring (TDM) is critical for managing pharmacokinetic variability and optimizing individualized therapy, particularly during public health crises such as the COVID-19 pandemic. Herein, we optimized integrated m...

Ultrasound as the New Stethoscope: A Journey From Just Locating Fluid to Assessing Haemodynamics and Venous Congestion.

British journal of hospital medicine (London, England : 2005)
Point-of-care ultrasound (POCUS) has evolved from a simple tool for fluid localization to a comprehensive modality for hemodynamic assessment and real-time clinical decision-making. The Bedside Lung Ultrasound in Emergency (BLUE) protocol enables cli...

Emerging trends in AI-integrated optical biosensors for point-of-care diagnostics: current status and future prospects.

Chemical communications (Cambridge, England)
Optical biosensors have emerged as a transformative class of point-of-care diagnostic (POCD) devices, offering sensitive, specific, and rapid detection of diseases. The integration of optical biosensors with artificial intelligence (AI) brings a new ...

A Single-step Platinum Nanoparticle-Enhanced Lateral Flow Immunoassay Platform for Rapid Detection of Influenza A Virus.

ACS infectious diseases
Lateral flow immunoassays (LFIAs) are widely used point-of-care (POC) diagnostic tools, but their limited sensitivity can hinder reliable diagnoses. To address this limitation, we developed a novel POC diagnostic platform for the highly sensitive det...

AI-powered programmable wetting-delamination μPAD for point-of-care food safety detection.

Biosensors & bioelectronics
The widespread use of pesticides and genetically modified (GM) crops has greatly improved agricultural productivity and food security. However, excessive pesticide application and the presence of exogenous proteins from GM crops pose significant risk...

Design and implementation of a natural language processing system at the point of care: MiADE (medical information AI data extractor).

BMC medical informatics and decision making
BACKGROUND: Well-organised electronic health records (EHR) are essential for high quality patient care, but EHR user interfaces can be cumbersome for entry of structured information, resulting in the majority of information being in free text rather ...

Wearable Point-of-Care Biosensor for Biomolecular Assay in Health Monitoring.

ACS applied bio materials
Wearable biosensors represent a significant advancement in preventive health monitoring by enabling early disease detection through real-time bioanalysis. This review examines the evolution of point-of-care testing (POCT), with a focus on materials, ...