Subcortical and insula functional connectivity aberrations and clinical implications in first-episode schizophrenia.

Journal: Asian journal of psychiatry
PMID: 39591757

Abstract

INTRODUCTION: Schizophrenia is a complex mental disorder whose pathophysiology remains elusive, particularly in the roles of subcortex. This study aims to explore the role of subcortex and insula and their relationship with symptom changes in first-episode schizophrenia (FES) patients by utilizing machine learning algorithms and functional connectivity (FC).

Authors

  • Bixin Wang
    Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China.
  • Meng Zhang
    College of Software, Beihang University, Beijing, China.
  • Fengmei Fan
    Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China.
  • Chunyu Yuan
    Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China.
  • Zhiren Wang
    Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China.
  • Yunlong Tan
    Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China.
  • Shuping Tan
    Psychiatry Research Center, Peking University Huilonguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing, 100096, China.

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