AIMC Topic: Insular Cortex

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Heterogeneity of human insular cortex: five principles of functional organization across multiple cognitive domains.

Brain structure & function
The insular cortex serves as a critical hub for human cognition, but how its anatomically distinct subregions coordinate diverse cognitive, emotional, and social functions remains unclear. Using the Human Connectome Project's multi-task fMRI dataset ...

Neurometabolic predictors of mental effort in the frontal cortex.

Translational psychiatry
Motivation drives individuals to overcome costs to achieve desired outcomes, such as rewards or avoidance of punishment, with significant variability across individuals. The dorsomedial prefrontal cortex/dorsal anterior cingulate cortex (dmPFC/dACC) ...

Increased GM-WM in a prefrontal network and decreased GM in the insula and the precuneus are associated with reappraisal usage and reduced perceived stress: A data fusion approach.

Neuropsychologia
Emotion regulation plays a crucial role in mental health, and difficulties in regulating emotions can contribute to psychological disorders. While reappraisal and suppression are well-studied strategies, the joint contributions of gray matter (GM) an...

Subcortical and insula functional connectivity aberrations and clinical implications in first-episode schizophrenia.

Asian journal of psychiatry
INTRODUCTION: Schizophrenia is a complex mental disorder whose pathophysiology remains elusive, particularly in the roles of subcortex. This study aims to explore the role of subcortex and insula and their relationship with symptom changes in first-e...

Preparatory activity of anterior insula predicts conflict errors: integrating convolutional neural networks and neural mass models.

Scientific reports
Preparatory brain activity is a cornerstone of proactive cognitive control, a top-down process optimizing attention, perception, and inhibition, fostering cognitive flexibility and adaptive attention control in the human brain. In this study, we prop...