Prognostic value of glycaemic variability for mortality in critically ill atrial fibrillation patients and mortality prediction model using machine learning.

Journal: Cardiovascular diabetology
PMID:

Abstract

BACKGROUND: The burden of atrial fibrillation (AF) in the intensive care unit (ICU) remains heavy. Glycaemic control is important in the AF management. Glycaemic variability (GV), an emerging marker of glycaemic control, is associated with unfavourable prognosis, and abnormal GV is prevalent in ICUs. However, the impact of GV on the prognosis of AF patients in the ICU remains uncertain. This study aimed to evaluate the relationship between GV and all-cause mortality after ICU admission at short-, medium-, and long-term intervals in AF patients.

Authors

  • Yang Chen
    Orthopedics Department of the First Affiliated Hospital of Tsinghua University, Beijing, China.
  • Zhengkun Yang
    Department of Cardiology, Tianjin Medical University General Hospital, Heping District, Tianjin, People's Republic of China.
  • Yang Liu
    Department of Computer Science, Hong Kong Baptist University, Hong Kong, China.
  • Ying Gue
    Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, United Kingdom; The Department of Cardiovascular and Metabolic Medicine, University of Liverpool, United Kingdom.
  • Ziyi Zhong
    Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.
  • Tao Chen
    School of Automation, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, China.
  • Feifan Wang
    Gastrointestinal Disease Diagnosis and Treatment Center, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, 050000, China.
  • Garry McDowell
    Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.
  • Bi Huang
    School of Big Data and Intelligent Engineering, Southwest Forestry University, Kunming, China.
  • Gregory Y H Lip
    Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, L69 3BX Liverpool, UK.