AI-derived automated quantification of cardiac chambers and myocardium from non-contrast CT: Prediction of major adverse cardiovascular events in asymptomatic subjects.

Journal: Atherosclerosis
PMID:

Abstract

BACKGROUND AND AIMS: The significance of left ventricular mass and chamber volumes from non-contrast computed tomography (CT) for predicting major adverse cardiovascular events (MACE) has not been studied. Our objective was to evaluate the role of artificial intelligence-enabled multi-chamber cardiac volumetry from non-contrast CT for long-term risk stratification in asymptomatic subjects without known coronary artery disease.

Authors

  • Aryabod Razipour
    Biomedical Imaging Research Institute (P.A.M., F.C., X.C., M.G., A.R., D.D.), Cedars-Sinai Medical Center, Los Angeles, CA.
  • Kajetan Grodecki
    Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
  • Nipun Manral
    Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Jolien Geers
    Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA (R.J.J.M., N.M., A.L., A.S., C.P., A.K., P.M., A.R., K.G., A.C.K., D.H., K.K., G.F.T., J.G., H.G., S.C., D.S.B., P.J.S., D.D.).
  • Heidi Gransar
    Departments of Imaging, Medicine, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.
  • Aakash Shanbhag
    Division of Artificial Intelligence, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Robert J H Miller
    Department of Imaging and Medicine and the Smidt Heart Institute (E.E., S.C., H.G., S.C., R.J.H.M., P.J.S., B.K.T., D.S.B.), Cedars-Sinai Medical Center, Los Angeles, CA.
  • Alan Rozanski
    Division of Cardiology, Mount Sinai St Lukes Hospital, New York, NY (A.R.).
  • Daniel S Berman
    Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Piotr J Slomka
    Department of Imaging, Medicine, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California Piotr.Slomka@cshs.org.
  • Damini Dey
    Departments of Imaging and Medicine, and Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Taper A238, Los Angeles, CA, 90048, USA.