Optimizing the management of immune-related adverse events and survival in patients with thoracic cancer receiving immunotherapy through artificial intelligence (electronic patient-reported outcomes): The IMPATHI study.

Journal: Bulletin du cancer
PMID: 39701887

Abstract

INTRODUCTION: The lung cancer continues to be the primary cause of cancer-related deaths, despite significant advancements in treatment through the introduction of immunological checkpoint inhibitors (ICI). These inhibitors, initially used as monotherapy, are now employed in combined therapies, resulting in improved survival rates. The ICI function by restoring T-cell activity to target tumor cells, but may lead to undesirable immune-related adverse events (irAE), necessitating careful management.

Authors

  • Serge Amouin
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Laurent Brureau
    Department of Urology, CHU de Pointe-à-Pitre, University of Antilles, 97110, Pointe-à-Pitre, France.
  • Charles Parnot
    Cureety, 33, rue de l'Amirauté, Dinan, France.
  • Hugo Picchi
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Audrey Le Roy
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Aline Barhli
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Marie-Anne Audisio
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Marie Pautas
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Juliette Brezun
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Antoine Schernberg
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France.
  • Hélène Vanquaethem
    Department of Internal Medicine, Military Hospital Bégin, Saint-Mandé, France.
  • Carole Helissey
    Department of Medical Oncology and Clinical Research Unit, Military Hospital Bégin, Saint-Mandé, France. Electronic address: carole.helissey@gmail.com.

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