Combined inflammation-related biomarkers and clinicopathological features for the prognosis of stage II/III colorectal cancer by machine learning.

Journal: BMC cancer
PMID: 39696042

Abstract

BACKGROUND: Inflammation-related biomarkers, such as systemic inflammation score (SIS) and neutrophil-lymphocyte ratio (NLR), are associated with colorectal cancer prognosis. However, the combined role of SIS, NLR, and clinicopathological factors in stage II/III colorectal cancer remains unclear. This study developed a nomogram to predict long-term prognosis for these patients.

Authors

  • Lei Liang
    Department of Oncology, First Affiliated Hospital of Kunming Medical University, Kunming, China.
  • Ning Xu
    Department of Clinical Laboratory The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming China.
  • Lanfei Ding
    Department of Emergency, The Second People's Hospital of Honghe Prefecture, Jianshui, 654300, China.
  • Xin Li
    Veterinary Diagnostic Center, Shanghai Animal Disease Control Center, Shanghai, China.
  • Chengxun Jiang
    Department of General Surgery, The Third People's Hospital of Honghe Prefecture, Gejiu, 661000, China.
  • Jianhua Zhang
  • Jun Yang
    Cardiovascular Endocrinology Laboratory, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Medicine, Monash University, Clayton, Victoria, Australia.

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