Dual biomarkers CT-based deep learning model incorporating intrathoracic fat for discriminating benign and malignant pulmonary nodules in multi-center cohorts.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PMID: 39689571

Abstract

BACKGROUND: Recent studies in the field of lung cancer have emphasized the important role of body composition, particularly fatty tissue, as a prognostic factor. However, there is still a lack of practice in combining fatty tissue to discriminate benign and malignant pulmonary nodules.

Authors

  • Shidi Miao
    School of Computer Science and Technology, Harbin University of Science and Technology, Harbin, China.
  • Qi Dong
    Institute of Biomechanics and Rehabilitation Engineering, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P.R.China;Shanghai Engineering Research Center of Assistive Devices, Shanghai 200093, P.R.China;Key Laboratory of Nerve Function Information and Rehabilitation Engineering, Shanghai 200093, P.R.China.
  • Le Liu
    Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Qifan Xuan
    School of Computer Science and Technology, Harbin University of Science and Technology, Harbin, China.
  • Yunfei An
    School of Computer Science and Technology, Harbin University of Science and Technology, Harbin, PR China.
  • Hongzhuo Qi
    School of Computer Science and Technology, Harbin University of Science and Technology, Harbin, China.
  • Qiujun Wang
    Department of General Practice, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.
  • Zengyao Liu
    Department of Interventional Medicine, The First Affiliated Hospital, Harbin Medical University, Harbin, China.
  • Ruitao Wang
    Department of Internal Medicine, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, China.

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