MRI classification of progressive supranuclear palsy, Parkinson disease and controls using deep learning and machine learning algorithms for the identification of regions and tracts of interest as potential biomarkers.

Journal: Computers in biology and medicine
PMID:

Abstract

BACKGROUND: Quantitative magnetic resonance imaging (MRI) analysis has shown promise in differentiating neurodegenerative Parkinsonian syndromes and has significantly advanced our understanding of diseases like progressive supranuclear palsy (PSP) in recent years.

Authors

  • Heiko Volkmann
    Department of Neurology, University of Ulm, Ulm, Germany. Electronic address: heiko.volkmann@uni-ulm.de.
  • Günter U Höglinger
    Department of Neurology, University Hospital Gießen and Marburg, Marburg, Germany.
  • Georg Grön
    Section for Neuropsychology and Functional Imaging, Dept. of Psychiatry III, University of Ulm, Germany. Electronic address: georg.groen@uni-ulm.de.
  • Lavinia A Bârlescu
    Department of Neurology, University of Ulm, Ulm, Germany. Electronic address: lavinia.barlescu@uni-ulm.de.
  • Hans-Peter Müller
    Department of Neurology, University of Ulm, Ulm, Germany.
  • Jan Kassubek
    Department of Neurology, University of Ulm, Ulm, Germany. jan.kassubek@uni-ulm.de.