Development and Validation of Multiparametric MRI-based Interpretable Deep Learning Radiomics Fusion Model for Predicting Lymph Node Metastasis and Prognosis in Rectal Cancer: A Two-center Study.

Journal: Academic radiology
PMID:

Abstract

RATIONALE AND OBJECTIVES: To develop interpretable machine learning models that utilize deep learning (DL) and radiomics based on multiparametric Magnetic resonance imaging (MRI) to predict preoperative lymph node (LN) metastasis in rectal cancer.

Authors

  • Yunjun Yang
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. yyjunjim@163.com.
  • Kaiting Han
    Department of Radiology, The First People's Hospital of Foshan, Foshan, China (Y.Y., K.H., Z.X., H.Z., J.H., Z.X.).
  • Zhenyu Xu
    Department of Urology, The Affiliated Hospital of Nanjing University of Traditional Chinese Medicine: Traditional Chinese Medicine Hospital of Kunshan, Kunshan, China.
  • Zhiping Cai
    College of Computer, National University of Defense Technology, Changsha, China. Electronic address: zpcai@nudt.edu.cn.
  • Hai Zhao
  • Julu Hong
    Department of Radiology, The First People's Hospital of Foshan, Foshan, China (Y.Y., K.H., Z.X., H.Z., J.H., Z.X.).
  • Jiawei Pan
    Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
  • Li Guo
    Department of Dental Implantology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, China.
  • Weijun Huang
  • Qiugen Hu
    Department of Radiology, Shunde Hospital, Southern Medical University, Foshan, China.
  • Zhifeng Xu
    College of Plant Protection, Southwest University, Chongqing, China.