Lung nodule classification using radiomics model trained on degraded SDCT images.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: Low-dose computed tomography (LDCT) screening has shown promise in reducing lung cancer mortality; however, it suffers from high false positive rates and a scarcity of available annotated datasets. To overcome these challenges, we propose a novel approach using synthetic LDCT images generated from standard-dose CT (SDCT) scans from the LIDC-IDRI dataset. Our objective is to develop and validate an interpretable radiomics-based model for distinguishing likely benign from likely malignant pulmonary nodules.

Authors

  • Jiaying Liu
  • Anna Corti
    Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milan, Italy.
  • Valentina D A Corino
    Department of Electronics, Information and Bioengineering (DEIB), Politecnico Di Milano, Via Golgi 39, 20133, Milan, Italy.
  • Luca Mainardi
    Department of ElectronicsInformation and BioengineeringPolitecnico di Milano 20133 Milan Italy.