Automated Segmentation of MRI White Matter Hyperintensities in 8421 Patients with Acute Ischemic Stroke.

Journal: AJNR. American journal of neuroradiology
PMID:

Abstract

BACKGROUND AND PURPOSE: To date, only a few small studies have attempted deep learning-based automatic segmentation of white matter hyperintensity (WMH) lesions in patients with cerebral infarction; this issue is complicated because stroke-related lesions can obscure WMH borders. We developed and validated deep learning algorithms to segment WMH lesions accurately in patients with cerebral infarction using multisite data sets involving 8421 patients with acute ischemic stroke.

Authors

  • Hosung Kim
    Laboratory of Neuro Imaging, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA. Electronic address: hosung.kim@loni.usc.edu.
  • Wi-Sun Ryu
    Artificial Intelligence Research Center, JLK Inc., 5 Teheran-ro 33-gil, Seoul, Republic of Korea. wisunryu@gmail.com.
  • Dawid Schellingerhout
    Departments of Cancer Systems Imaging and Neuroradiology, MD Anderson Cancer Center, The University of Texas, Houston, Texas, USA.
  • Jonghyeok Park
    Artificial Intelligence Research Center (W.-S.R, J.P.), JLK Inc, Seoul, Republic of Korea.
  • Jinyong Chung
    National Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
  • Sang-Wuk Jeong
    National Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
  • Dong-Seok Gwak
    National Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
  • Beom Joon Kim
    Departments of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
  • Joon-Tae Kim
    Department of Neurology (J.-T.K., M.S.P.,), Chonnam National University Hospital, Gwangju, Republic of Korea.
  • Keun-Sik Hong
    Department of Neurology (K.-S.H., Y,-J.C.), Inje University Ilsan Paik Hospital, Goyang, Republic of Korea.
  • Kyung Bok Lee
    Department of Neurology (K.B.L.), Soonchunhyang University Hospital, Seoul, Republic of Korea.
  • Tai Hwan Park
    Department of Neurology (T.H.P.), Seoul Medical Center, Seoul, Republic of Korea.
  • Jong-Moo Park
    Department of Neurology (J.-M.P.), Uijeongbu Eulji Medical Center, Uijeongbu, Republic of Korea.
  • Kyusik Kang
    Department of Neurology (K.K.), Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Republic of Korea.
  • Yong-Jin Cho
    Department of Neurology (K.-S.H., Y,-J.C.), Inje University Ilsan Paik Hospital, Goyang, Republic of Korea.
  • Byung-Chul Lee
    Genoplan Korea Inc., Seoul, Republic of Korea. io@genoplan.com.
  • Kyung-Ho Yu
    Department of Neurology (B.-C.L., K.-H.Y., M.S.O.), Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
  • Mi Sun Oh
    Department of Neurology (B.-C.L., K.-H.Y., M.S.O.), Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
  • Soo Joo Lee
    Department of Neurology (S.J.L.), Eulji University Hospital, Daejeon, Republic of Korea.
  • Jae-Kwan Cha
    Department of Neurology (J.-K.C., D.-H.K.), Dong-A University Hospital, Busan, Republic of Korea.
  • Dae-Hyun Kim
    Department of Neurology (J.-K.C., D.-H.K.), Dong-A University Hospital, Busan, Republic of Korea.
  • Jun Lee
    Nephrology Unit, Department of Medicine, Sarawak General Hospital, Sarawak, Malaysia.
  • Man Seok Park
    Department of Neurology (J.-T.K., M.S.P.,), Chonnam National University Hospital, Gwangju, Republic of Korea.
  • Hee-Joon Bae
  • Dong-Eog Kim
    National Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea kdongeog@duih.org.