The role and machine learning analysis of mitochondrial autophagy-related gene expression in lung adenocarcinoma.

Journal: Frontiers in immunology
PMID: 40313958

Abstract

OBJECTIVE: Lung adenocarcinoma (LUAD) continues to be a primary cause of cancer-related mortality globally, highlighting the urgent need for novel insights finto its molecular mechanisms. This study aims to investigate the relationship between gene expression and mitophagy in LUAD, with an emphasis on identifying key biomarkers and elucidating their roles in tumorigenesis and immune cell infiltration.

Authors

  • Binyu Wang
    Department of Clinical Laboratory, The First Affiliated Hospital of Huzhou University, The First People's Hospital of Huzhou City, Zhejiang Province, China.
  • Di Liu
    Laboratory of Nutrition and Functional Food, College of Food Science and Engineering, Jilin University, Changchun, China.
  • Danfei Shi
    Department of Pathology, The First Affiliated Hospital of Huzhou University, The First People's Hospital of Huzhou City, Zhejiang Province, China.
  • Xinmin Li
    Department of Clinical Laboratory, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.
  • Yong Li
    Department of Surgical Sciences, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI, United States.

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