Revealing gut microbiota biomarkers associated with melanoma immunotherapy response and key bacteria-fungi interaction relationships: evidence from metagenomics, machine learning, and SHAP methodology.

Abstract

Authors

• Yuhang Zhou
  Cardeza Foundation for Hematologic Research, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States.
• Wenjie Han
  Shenyang Aircraft Corporation, Shenyang 110136, China.
• Yun Feng
  Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
• Yue Wang
  Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
• Xiaolin Liu
  Department of Physics, Shanghai University of Electric Power, Shanghai 200090, China. Electronic address: xlliu@shiep.edu.cn.
• Tao Sun
  Janssen Research & Development, LLC, Raritan, NJ, USA.
• Junnan Xu
  State Key Laboratory of Organ Failure Research, Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong Province Key Laboratory of Psychiatric Disorders, Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.

Keywords

External Resources