Paclitaxel-loaded niosomes for intravenous administration: pharmacokinetics and tissue distribution in rats.

Journal: Turkish journal of medical sciences
PMID:

Abstract

BACKGROUND/AIM: The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats.

Authors

  • Zerrin Sezgin Bayindir
  • Arzu Beşikci Be
  • Nilüfer Yüksel