AIMC Topic: Rats, Wistar
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Altered aminoacid and lipid metabolism in a rat orofacial inflammation model determined by omics approach: potential role in trigeminal sensitisation.
The journal of headache and pain
May 8, 2025
BACKGROUND: Trigeminal activation and sensitisation involved in chronic inflammatory orofacial pain share several similarities with headaches, including migraine. Therefore, understanding the pathophysiological mechanisms is important to determine no...
Safety assessment of the ethanolic extract of Siparuna guianensis: Cell viability, molecular risk predictions and toxicity risk for acute and sub-chronic oral ingestion.
Journal of ethnopharmacology
Apr 5, 2025
ETHNOPHARMACOLOGICAL RELEVANCE: The species Siparuna guianensis Aublet (family Siparunaceae) is traditionally used by indigenous peoples and riverine communities in Central and South America to treat migraines, flu, respiratory diseases, fever, pain,...
Does infection alter antifungal distribution: an animal model exploring pharmacokinetic changes.
Future microbiology
Apr 3, 2025
AIM: Assessing the disseminated meningitis caused by in Wistar rats and its impact on antifungal distribution by microdialysis (µD).
Robust resolution improvement of 3D UTE-MR angiogram of normal vasculatures using super-resolution convolutional neural network.
Scientific reports
Mar 18, 2025
Contrast-enhanced UTE-MRA provides detailed angiographic information but at the cost of prolonged scanning periods, which may impose moving artifacts and affect the promptness of diagnosis and treatment of time-sensitive diseases like stroke. This st...
Of rats and robots: A mutual learning paradigm.
Journal of the experimental analysis of behavior
Mar 12, 2025
Robots are increasingly used alongside Skinner boxes to train animals in operant conditioning tasks. Similarly, animals are being employed in artificial intelligence research to train various algorithms. However, both types of experiments rely on uni...
Cytotoxicity, Antiadipogenic, Low-Density Lipoprotein Oxidation Inhibitory Activities, and Acute Toxicity Study of Hydroethanolic Leaf and Bark Extracts.
TheScientificWorldJournal
Dec 17, 2024
Obesity is increasingly taking an important stage as a cause of death worldwide, and interventions with a good cost-effectiveness ratio are needed. is one of these natural products with health benefits. Objective. The present study evaluated the cy...
Estrogen-mediated modulation of sterile inflammatory markers and baroreflex sensitivity in ovariectomized female Wistar rats.
Archives of endocrinology and metabolism
Nov 6, 2024
OBJECTIVE: This study aims to explore the role of estrogen in providing cardioprotective benefits to premenopausal women, examining how hormonal differences between sexes influence the prevalence of cardiovascular diseases (CVDs) in women.
Chemical composition alterations in rat brain hypothalamus induced by irisin administration using spectroscopic and machine learning techniques.
Analytical biochemistry
Oct 16, 2024
This study employed Fourier transform infrared (FTIR) spectroscopy to determine the chemical composition of brain tissues and the changes induced by irisin at doses of 50 mg and 100 mg. Brain tissues were collected from control rats and those adminis...
Lipids balance as a spectroscopy marker of diabetes. Analysis of FTIR spectra by 2D correlation and machine learning analyses.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jun 13, 2024
The number of people suffering from type 2 diabetes has rapidly increased. Taking into account, that elevated intracellular lipid concentrations, as well as their metabolism, are correlated with diminished insulin sensitivity, in this study we would ...
Automatic liver segmentation and assessment of liver fibrosis using deep learning with MR T1-weighted images in rats.
Magnetic resonance imaging
Dec 24, 2023
OBJECTIVES: To validate the performance of nnU-Net in segmentation and CNN in classification for liver fibrosis using T1-weighted images.
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