Unveiling the role of PANoptosis-related genes in breast cancer: an integrated study by multi-omics analysis and machine learning algorithms.

Journal: Breast cancer research and treatment
PMID:

Abstract

BACKGROUND: The heterogeneity of breast cancer (BC) necessitates the identification of novel subtypes and prognostic models to enhance patient stratification and treatment strategies. This study aims to identify novel BC subtypes based on PANoptosis-related genes (PRGs) and construct a robust prognostic model to guide individualized treatment strategies.

Authors

  • Gang Liu
    Department of Interventional Radiology, Qinghai Red Cross Hospital, Xining, Qinghai, China.
  • Liang-Zhi Pan
    Party Committee Office, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, China.
  • Jie Chen
    School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, China.
  • Jianying Ma
    Department of Breast Surgery, Thyroid Surgery, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, No.141, Tianjin Road, Huangshi, 435000, Hubei, China. majianying2015@sina.com.