Exploring the triglyceride-glucose index's role in depression and cognitive dysfunction: Evidence from NHANES with machine learning support.

Journal: Journal of affective disorders
PMID:

Abstract

BACKGROUND: Depression and cognitive impairments are prevalent among older adults, with evidence suggesting potential links to obesity and lipid metabolism disturbances. This study investigates the relationships between the triglyceride-glucose (TyG) index, body mass index (BMI), depression, and cognitive dysfunction in older adults, leveraging data from the NHANES survey and employing machine learning techniques.

Authors

  • Chao Ding
    Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Renjie Lu
    Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Zhiyu Kong
    South China University of Technology, Guangzhou, China.
  • Rong Huang
    School of Nursing, Chuanbei Medical College, Nanchong, China.