Exploring the Mechanisms of Sanguinarine in the Treatment of Osteoporosis by Integrating Network Pharmacology Analysis and Deep Learning Technology.

Journal: Current computer-aided drug design
PMID:

Abstract

BACKGROUND: Sanguinarine (SAN) has been reported to have antioxidant, antiinflammatory, and antimicrobial activities with potential for the treatment of osteoporosis (OP).

Authors

  • Yonghong Tang
    Department of Orthopedics, The Sixth People's Hospital of Zhuji, Zhuji, Zhejiang, China.
  • Daoqing Zhou
    Department of Orthopedics, Pan'an Hospital of Traditional Chinese Medicine, Jinhua, Zhejiang, China.
  • Fengping Gan
    Department of Ultrasound, Affiliated Hospital, Jiujiang Medical College, Jiujiang, 332000, Jiangxi, China.
  • Zhicheng Yao
    The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
  • Yuqing Zeng
    The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.