An interpretable deep-learning approach to detect biomarkers in anxious-depressed symptoms from prefrontal fNIRS signals during an autobiographical memory test.

Journal: Asian journal of psychiatry
PMID:

Abstract

BACKGROUND: Individuals with anxious-depressed (AD) symptoms have more severe mood disorders and cognitive impairment than those with non-anxious depression (NAD) symptoms. Therefore, it is important to clarify the underlying neurophysiology of these two symptom groups to optimize treatment.

Authors

  • Yan Zhang
    Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, 110032, China.
  • Yawen Xu
    Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Yihang Cheng
    Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, Guangdong, China.
  • Yihong Zhao
    School of Nursing, Columbia University, New York, NY, United States.
  • Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Hui Shi
    Department of Rheumatology and Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.