Artificial intelligence-driven microsatellite instability profiling reveals distinctive genetic features in patients with lung cancer.

Journal: Cancer
PMID: 40297960

Abstract

BACKGROUND: Microsatellite instability (MSI) has emerged as a predictive biomarker for immunotherapy response in various cancers, but its role in non-small cell lung cancer (NSCLC) is not fully understood.

Authors

  • Quentin Dominique Thomas
    Department of Medical Oncology, Institute du Cancer de Montpellier, Montpellier University, Montpellier, France.
  • Julie Adèle Vendrell
    Solid Tumor Laboratory, Department of Pathology and Oncobiology, Montpellier University Hospital Montpellier, Arnaud de Villeneuve Hospital, Montpellier, France.
  • Lakhdar Khellaf
    Department of Pathology, Institute du Cancer de Montpellier, Montpellier University, Montpellier, France.
  • Sarah Cavaillon
    Department of Medical Oncology, Institute du Cancer de Montpellier, Montpellier University, Montpellier, France.
  • Xavier Quantin
    Department of Medical Oncology, Institute du Cancer de Montpellier, Montpellier University, Montpellier, France.
  • Jérôme Solassol
    Solid Tumor Laboratory, Department of Pathology and Oncobiology, Montpellier University Hospital Montpellier, Arnaud de Villeneuve Hospital, Montpellier, France.
  • Simon Cabello-Aguilar
    Solid Tumor Laboratory, Department of Pathology and Oncobiology, Montpellier University Hospital Montpellier, Arnaud de Villeneuve Hospital, Montpellier, France.

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