Feasibility exploration of myocardial blood flow synthesis from a simulated static myocardial computed tomography perfusion via a deep neural network.

Journal: Journal of X-ray science and technology
PMID:

Abstract

BACKGROUND:  Myocardial blood flow (MBF) provides important diagnostic information for myocardial ischemia. However, dynamic computed tomography perfusion (CTP) needed for MBF involves multiple exposures, leading to high radiation doses.

Authors

  • Jun Dong
    Suzhou Institute of Nanotech and Nanobionics, Chinese Academy of Sciences, Suzhou 215123, China.
  • Runjianya Ling
    From the Departments of Radiology (M.L., LY., J.Z.) and Cardiology (W.Y.), Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Rd, Shanghai 200080, China; Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China (R.L.); and Shanghai United Imaging Intelligence, Shanghai, China (Z.C., D.W.).
  • Zhenxing Huang
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Yidan Xu
    Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
  • Haiyan Wang
    College of Chemistry and Material Science, Shandong Agricultural University, Tai'an 271018, PR China.
  • Zixiang Chen
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, People's Republic of China.
  • Meiyong Huang
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
  • Vladimir Stankovic
    Department of Electronic and Electrical Engineering, University of Strathclyde, Glasgow G1 1XW, UK.
  • Jiayin Zhang
    Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
  • Zhanli Hu
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.