AIMC Topic: Myocardial Ischemia

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Developing cardiac digital twin populations powered by machine learning provides electrophysiological insights in conduction and repolarization.

Nature cardiovascular research
Large-cohort imaging and diagnostic studies often assess cardiac function but overlook underlying biological mechanisms. Cardiac digital twins (CDTs) are personalized physics-constrained and physiology-constrained in silico representations, uncoverin...

Feasibility exploration of myocardial blood flow synthesis from a simulated static myocardial computed tomography perfusion via a deep neural network.

Journal of X-ray science and technology
BACKGROUND:  Myocardial blood flow (MBF) provides important diagnostic information for myocardial ischemia. However, dynamic computed tomography perfusion (CTP) needed for MBF involves multiple exposures, leading to high radiation doses.

Artificial Intelligence in Ischemic Heart Disease Prevention.

Current cardiology reports
PURPOSE OF REVIEW: This review discusses the transformative potential of artificial intelligence (AI) in ischemic heart disease (IHD) prevention. It explores advancements of AI in predictive modeling, biomarker discovery, and cardiovascular imaging. ...

Noninvasive machine-learning models for the detection of lesion-specific ischemia in patients with stable angina with intermediate stenosis severity on coronary CT angiography.

Physical and engineering sciences in medicine
This study proposed noninvasive machine-learning models for the detection of lesion-specific ischemia (LSI) in patients with stable angina with intermediate stenosis severity based on coronary computed tomography (CT) angiography. This single-center ...

Analysis of the Predictors of Mortality from Ischemic Heart Diseases in the Southern Region of Brazil: A Geographic Machine-Learning-Based Study.

Global heart
BACKGROUND: Mortality due to ischemic heart disease (IHD) is heterogeneously distributed globally, and identifying the sites most affected by it is essential in developing strategies to mitigate the impact of the disease, despite the complexity resul...

Noninvasive and fast method of calculation for instantaneous wave-free ratio based on haemodynamics and deep learning.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: Instantaneous wave-free ratio (iFR) is a new invasive indicator of myocardial ischaemia, and its diagnostic performance is as good as the "gold standard" of myocardial ischaemia diagnosis: fractional flow reserve (FFR). iFR...

Using machine learning to predict acute myocardial infarction and ischemic heart disease in primary care cardiovascular patients.

PloS one
BACKGROUND: Early recognition, which preferably happens in primary care, is the most important tool to combat cardiovascular disease (CVD). This study aims to predict acute myocardial infarction (AMI) and ischemic heart disease (IHD) using Machine Le...

Established machine learning models to predict readmission for elderly patients with ischemic heart disease.

Kardiologia polska
BACKGROUND: The contribution of clinical features associated with 30-day or 1-year readmission in elderly patients with ischemic heart disease (IHD) and whether these features can be used to predict the readmission risk of patients has not been studi...

Explainable deep-learning-based ischemia detection using hybrid O-15 HO perfusion positron emission tomography and computed tomography imaging with clinical data.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: We developed an explainable deep-learning (DL)-based classifier to identify flow-limiting coronary artery disease (CAD) by O-15 HO perfusion positron emission tomography computed tomography (PET/CT) and coronary CT angiography (CTA) imagi...