Large-cohort imaging and diagnostic studies often assess cardiac function but overlook underlying biological mechanisms. Cardiac digital twins (CDTs) are personalized physics-constrained and physiology-constrained in silico representations, uncoverin...
Journal of X-ray science and technology
Mar 3, 2025
BACKGROUND:  Myocardial blood flow (MBF) provides important diagnostic information for myocardial ischemia. However, dynamic computed tomography perfusion (CTP) needed for MBF involves multiple exposures, leading to high radiation doses.
PURPOSE OF REVIEW: This review discusses the transformative potential of artificial intelligence (AI) in ischemic heart disease (IHD) prevention. It explores advancements of AI in predictive modeling, biomarker discovery, and cardiovascular imaging. ...
Physical and engineering sciences in medicine
Dec 30, 2024
This study proposed noninvasive machine-learning models for the detection of lesion-specific ischemia (LSI) in patients with stable angina with intermediate stenosis severity based on coronary computed tomography (CT) angiography. This single-center ...
BACKGROUND: Mortality due to ischemic heart disease (IHD) is heterogeneously distributed globally, and identifying the sites most affected by it is essential in developing strategies to mitigate the impact of the disease, despite the complexity resul...
Computer methods and programs in biomedicine
Jul 23, 2024
BACKGROUND AND OBJECTIVES: Instantaneous wave-free ratio (iFR) is a new invasive indicator of myocardial ischaemia, and its diagnostic performance is as good as the "gold standard" of myocardial ischaemia diagnosis: fractional flow reserve (FFR). iFR...
BACKGROUND: Early recognition, which preferably happens in primary care, is the most important tool to combat cardiovascular disease (CVD). This study aims to predict acute myocardial infarction (AMI) and ischemic heart disease (IHD) using Machine Le...
BACKGROUND: The contribution of clinical features associated with 30-day or 1-year readmission in elderly patients with ischemic heart disease (IHD) and whether these features can be used to predict the readmission risk of patients has not been studi...
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Jun 8, 2024
BACKGROUND: We developed an explainable deep-learning (DL)-based classifier to identify flow-limiting coronary artery disease (CAD) by O-15 HO perfusion positron emission tomography computed tomography (PET/CT) and coronary CT angiography (CTA) imagi...
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