Unsupervised machine learning-based stratification and immune deconvolution of liver hepatocellular carcinoma.

Journal: BMC cancer
PMID:

Abstract

BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer and a leading cause of cancer-related deaths globally. The tumour microenvironment (TME) influences treatment response and prognosis, yet its heterogeneity remains unclear.

Authors

  • Mae Montserrat Reierson
    Cancer and Genomic Sciences, School of Medical Sciences, College of Medicine and Health, University of Birmingham, Birmingham, B15 2TT, UK.
  • Animesh Acharjee
    College of Medicine and Health, School of Medical Sciences, Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.