Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER): design and rationale for a decentralised, real-world cluster-randomised controlled trial and implementation study.

Journal: BMJ open
Published Date: May 21, 2025

Abstract

INTRODUCTION: Early detection of cardiovascular disease in primary care is a public health priority, for which the clinical and cost-effectiveness of an artificial intelligence-enabled stethoscope that detects left ventricular systolic dysfunction, atrial fibrillation and cardiac murmurs is unproven but potentially transformative.

Authors

  • Mihir A Kelshiker
    National Heart and Lung Institute and Centre for Cardiac Engineering, Imperial College London, London, UK; Imperial College Healthcare NHS Trust, London, UK.
  • Patrik Bachtiger
    Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Josephine Mansell
    National Heart and Lung Institute, Imperial College London, London, England, UK.
  • Daniel B Kramer
    Richard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
  • Saloni Nakhare
    National Heart and Lung Institute, Imperial College London, London, England, UK.
  • Melanie T Almonte
    National Heart and Lung Institute, Imperial College London, London, England, UK.
  • Abdullah Alrumayh
    National Heart and Lung Institute, Imperial College London, London, England, UK.
  • Camille F Petri
    National Heart and Lung Institute and Centre for Cardiac Engineering, Imperial College London, London, UK; UKRI Centre for Doctoral Training in AI for Healthcare, Imperial College London, London, UK.
  • Alexei Peters
    National Heart and Lung Institute, Imperial College London, London, England, UK.
  • Ceire Costelloe
    School of Public Health, Imperial College London, London, UK.
  • Emanuela Falaschetti
    Imperial Clinical Trials Unit, Imperial College London, London, England.
  • Carys Barton
    Imperial College Healthcare NHS Trust, London, England, UK.
  • Rasha Al-Lamee
    National Heart and Lung Institute, Imperial College London, London, England, UK.
  • Azeem Majeed
    Imperial College London, London, UK.
  • Carla M Plymen
    Imperial College Healthcare NHS Trust, London, UK.
  • Nicholas S Peters
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.

Keywords

External Resources

Popular Topics
Recent Journals