AIMC Topic: Multicenter Studies as Topic

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Prenatal detection of congenital heart defects using the deep learning-based image and video analysis: protocol for Clinical Artificial Intelligence in Fetal Echocardiography (CAIFE), an international multicentre multidisciplinary study.

BMJ open Jun 5, 2025
INTRODUCTION: Congenital heart defect (CHD) is a significant, rapidly emerging global problem in child health and a leading cause of neonatal and childhood death. Prenatal detection of CHDs with the help of ultrasound allows better perinatal manageme...
Humans Artificial Intelligence Pregnancy Multicenter Studies as Topic Video Recording Heart Defects, Congenital Fetal Heart Female Echocardiography Ultrasonography, Prenatal Deep Learning
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Active case finding using mobile vans with artificial intelligence aided radiology tests and sputum collection for rapid diagnostic tests to reduce tuberculosis prevalence among high-risk population in rural China: Protocol for a pragmatic trial.

PloS one Apr 11, 2025
BACKGROUND: Tuberculosis (TB) remains a significant public health challenge, particularly in rural areas of high-burden countries like China. Active case finding (ACF) and timely treatment have been proven effective in reducing TB prevalence, but the...
Humans Artificial Intelligence Tuberculosis Diagnostic Tests, Routine Pragmatic Clinical Trials as Topic Mobile Health Units Rapid Diagnostic Tests China Female Rural Population Adult Male Prevalence Multicenter Studies as Topic Sputum
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Artificial intelligence-based personalised rituximab treatment protocol in membranous nephropathy (iRITUX): protocol for a multicentre randomised control trial.

BMJ open Apr 2, 2025
INTRODUCTION: Membranous nephropathy is an autoimmune kidney disease and the most common cause of nephrotic syndrome in non-diabetic Caucasian adults. Rituximab is now recommended as first-line therapy for membranous nephropathy. However, Kidney Dise...
Nephrotic Syndrome Immunologic Factors Glomerulonephritis, Membranous France Rituximab Algorithms Prospective Studies Precision Medicine Female Adult Male Multicenter Studies as Topic Randomized Controlled Trials as Topic Humans Artificial Intelligence
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Does the alternating timing of rTMS combined with soft-hand rehabilitation robot affect the recovery of hand function in patients after stroke? A study protocol for a multicentre randomised controlled trial.

BMJ open Mar 3, 2025
INTRODUCTION: Combining repetitive transcranial magnetic stimulation (rTMS) with robotic training could result in more significant improvements in motor function than either treatment alone. The efficacy of this combination may depend on the sequenci...
Humans Female Time Factors Multicenter Studies as Topic Recovery of Function Randomized Controlled Trials as Topic Aged Adult Male Middle Aged Stroke Rehabilitation Transcranial Magnetic Stimulation Robotics Single-Blind Method Hand Stroke
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A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherapy: the ASTuTE protocol.

BMC cancer Feb 13, 2025
BACKGROUND: Androgen deprivation therapy (ADT) improves outcomes in men undergoing definitive radiotherapy for prostate cancer but carries significant toxicities. Clinical parameters alone are insufficient to accurately identify patients who will der...
Prostatic Neoplasms Androgen Antagonists Biomarkers, Tumor Male Australia Multicenter Studies as Topic Humans Artificial Intelligence Prognosis
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Clinical validation of an artificial intelligence-based decision support system for diagnosis and risk stratification of heart failure (STRATIFYHF): a protocol for a prospective, multicentre longitudinal study.

BMJ open Jan 7, 2025
INTRODUCTION: Heart failure (HF) is a complex clinical syndrome. Accurate risk stratification and early diagnosis of HF are challenging as its signs and symptoms are non-specific. We propose to address this global challenge by developing the STRATIFY...
Longitudinal Studies Observational Studies as Topic Multicenter Studies as Topic Heart Failure Validation Studies as Topic Male Middle Aged Risk Assessment Decision Support Systems, Clinical Prognosis Female Aged Humans Artificial Intelligence Prospective Studies
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Healthy core: Harmonizing brain MRI for supporting multicenter migraine classification studies.

PloS one Dec 31, 2024
Multicenter and multi-scanner imaging studies may be necessary to ensure sufficiently large sample sizes for developing accurate predictive models. However, multicenter studies, incorporating varying research participant characteristics, MRI scanners...
Case-Control Studies Female Magnetic Resonance Imaging Adult Humans Migraine Disorders Male Machine Learning Multicenter Studies as Topic Middle Aged Brain
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Rationale and design of the GOLDEN BRIDGE II: a cluster-randomised multifaceted intervention trial of an artificial intelligence-based cerebrovascular disease clinical decision support system to improve stroke outcomes and care quality in China.

Stroke and vascular neurology Dec 30, 2024
BACKGROUND: Given the swift advancements in artificial intelligence (AI), the utilisation of AI-based clinical decision support systems (AI-CDSSs) has become increasingly prevalent in the medical domain, particularly in the management of cerebrovascu...
Treatment Outcome Multicenter Studies as Topic Randomized Controlled Trials as Topic Ischemic Stroke Quality Improvement Quality Indicators, Health Care Male China Time Factors Decision Support Systems, Clinical Humans Artificial Intelligence Clinical Decision-Making Female
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Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial (phase II).

PloS one Dec 27, 2024
BACKGROUND: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diar...
Gastrointestinal Microbiome Fecal Microbiota Transplantation Dysbiosis Multicenter Studies as Topic Humans Female Anti-Bacterial Agents Male Randomized Controlled Trials as Topic Prospective Studies Diarrhea Critical Illness Clinical Trials, Phase II as Topic Feces
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Detecting irregularities in randomized controlled trials using machine learning.

Clinical trials (London, England) Nov 25, 2024
BACKGROUND: Over the course of a clinical trial, irregularities may arise in the data. Trialists implement human-intensive, expensive central statistical monitoring procedures to identify and correct these irregularities before the results of the tri...
Algorithms Humans Multicenter Studies as Topic Machine Learning Randomized Controlled Trials as Topic Data Interpretation, Statistical
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