Early efficacy observation of suspended lower-limb rehabilitation robot-assisted therapy in patients with intensive care unit-acquired weakness: a study protocol for a self-controlled randomised controlled trial.

Journal: BMJ open

Published Date: May 30, 2025

Abstract

INTRODUCTION: Intensive care unit-acquired weakness (ICUAW) is a common and severe complication in critically ill patients, associated with high morbidity and poor prognosis. Despite increasing focus on ICUAW, definitive diagnostic and therapeutic strategies remain absent. Early mobilisation has been demonstrated as an effective intervention for preventing and alleviating ICUAW. This study aims to evaluate the early-stage efficacy of suspended lower-limb rehabilitation robot-assisted therapy in patients with ICUAW.

Authors

Lifan Xu

Department of Rehabilitation Medicine, Changhai Hospital, Shanghai, China.
Heng Wu

First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China.
Xiaonan Huang

Soft Machines Lab, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA. cmajidi@andrew.cmu.edu.
Jialiang Song

Department of Rehabilitation Medicine, Changhai Hospital, Shanghai, China.
Fanfu Fang

Department of Rehabilitation, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. Electronic address: fangfanfu@126.com.

Keywords

Adult Critical Illness Early Ambulation Female Humans Intensive Care Units Lower Extremity Male Middle Aged Muscle Weakness Randomized Controlled Trials as Topic Range of Motion, Articular Robotics

External Resources

View on PubMed Access via DOI PubMed (40447423)

Early efficacy observation of suspended lower-limb rehabilitation robot-assisted therapy in patients with intensive care unit-acquired weakness: a study protocol for a self-controlled randomised controlled trial.

Abstract

Authors

Keywords

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