Machine learning-based risk prediction model for neuropathic foot ulcers in patients with diabetic peripheral neuropathy.
Journal:
Journal of diabetes investigation
Published Date:
Mar 21, 2025
Abstract
BACKGROUND: Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes, marked by symptoms like hyperalgesia, numbness, and swelling that impair quality of life. Nerve conduction abnormalities in DPN significantly increase the risk of neuropathic foot ulcers (NFU), which can progress rapidly and lead to severe outcomes, including infection, gangrene, and amputation. Early prediction of NFU in DPN patients is crucial for timely intervention.