Physiological comparison of noninvasive ventilation and high-flow nasal oxygen on inspiratory efforts and tidal volumes after extubation: a randomized crossover trial.

Journal: Critical care (London, England)
PMID: 40341100

Abstract

BACKGROUND: Extubation failure leading to reintubation is associated with high mortality. In patients at high-risk of extubation failure, clinical practice guidelines recommend prophylactic non-invasive ventilation (NIV) over high-flow nasal oxygen (HFNO) immediately after extubation. However, the physiological effects supporting the beneficial effect of NIV have been poorly explored. We hypothesized that NIV may reduce patient inspiratory efforts to a greater extent than HFNO after extubation.

Authors

  • François Arrivé
    Centre Hospitalier Universitaire de Poitiers, Service de Médecine Intensive Réanimation, Poitiers, France.
  • Sylvain Le Pape
    Centre Hospitalier Universitaire de Poitiers, Service de Médecine Intensive Réanimation, Poitiers, France.
  • Alejandro Bruhn
    Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Adrien Pépin Lehalleur
    Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.
  • Clément Beuvon
    Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.
  • Samuel Tuffet
    Service de Réanimation, Centre Hospitalier Saint Joseph Saint Luc, Lyon, France.
  • Erik Etien
    ISAE-ENSMA Poitiers, LIAS, Université de Poitiers, Poitiers, France.
  • Laurent Rambault
    ISAE-ENSMA Poitiers, LIAS, Université de Poitiers, Poitiers, France.
  • Jean-Pierre Frat
    Centre Hospitalier Universitaire de Poitiers, Service de Médecine Intensive Réanimation, Poitiers, France.
  • Rémi Coudroy
    Centre Hospitalier Universitaire de Poitiers, Service de Médecine Intensive Réanimation, Poitiers, France.
  • Arnaud W Thille
    Centre Hospitalier Universitaire de Poitiers, Service de Médecine Intensive Réanimation, Poitiers, France.

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