Integrating bioinformatics and machine learning to unravel shared mechanisms and biomarkers in chronic obstructive pulmonary disease and type 2 diabetes.

Journal: Postgraduate medical journal
Published Date:

Abstract

BACKGROUND: Chronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) are on the rise. While there is evidence of a link between the two diseases, the pathophysiological mechanisms they share are not fully understood.

Authors

  • Shen Jiran
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China.
  • Wang Jiling
    Department of Infectious Diseases, Hefei Second People's Hospital, Heping Road 246, Hefei 230001, China.
  • Zhou Sijing
    Department of Occupational Disease, Hefei Third People's Hospital, Hefei Third Clinical College of Anhui Medical University, Wangjiang East Road 204, Hefei 230022, China.
  • Zhang Binbin
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China.
  • Li Pulin
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China.
  • Han Rui
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China.
  • Fei Guanghe
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China.
  • Cao Chao
    Department of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Ningbo, The First Affiliated Hospital of Ningbo University, 59 Liuting Road, Ningbo 315010, Zhejiang, China.
  • Wang Ran
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China.