Development of an immune-related gene signature applying Ridge method for improving immunotherapy responses and clinical outcomes in lung adenocarcinoma.

Journal: PeerJ
Published Date:

Abstract

BACKGROUND: Lung adenocarcinoma (LUAD) is a major cause of cancer mortality. Considering the critical role of tumor infiltrating lymphocytes in effective immunotherapy, this study was designed to screen molecular markers related to tumor infiltrating cells in LUAD, aiming to improve immunotherapy response during LUAD therapy.

Authors

  • Zhen Chen
    School of Basic Medicine, Qingdao University, Qingdao 266021, China.
  • Yongjun Zhang
    School of Information Engineering, Shandong Youth University of Political Science, Jinan, China.