Association between fibrinogen levels and prognosis in critically bleeding patients: exploration of the optimal therapeutic threshold.

Journal: European journal of trauma and emergency surgery : official publication of the European Trauma Society
Published Date: May 23, 2025

Abstract

BACKGROUND: Severe bleeding is a leading cause of ICU admission and mortality. Fibrinogen plays a crucial role in prognosis, yet optimal thresholds and supplementation targets remain unclear.

Authors

  • Bingkui Ren
    Department of Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
  • Yuping Zhang
    School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan 611731, PR China.
  • Siying Chen
    School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
  • Jinglong Dai
    Department of Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
  • Junci Chong
    Department of Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
  • Zhigang Chang
    Department of Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China. zhigangchang@hotmail.com.

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